Matondo,Ramadhan B2025-02-262025-02-262008https://www.suaire.sua.ac.tz/handle/123456789/6597ThesisLiver, the largest single organ in the body plays a central role in metabolism with a number of functions including, synthesis, storage and redistribution of carbohydrates, fats, and vitamins. Also, the liver produces large numbers of serum proteins including albumin, acute-phase proteins, enzymes and cofactors (1). Anatomically and functionally, the liver can be divided into hepatic lobules which are functional units and hexagonal in shape (Figure 1), (2).enSerum proteinsp53 and RbLiver cancerAlbuminEnzymes and cofactorsThesis