Browsing by Author "Ally, Mohamed Hamed Sango"

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Assessment of antimicrobial activity of velvet bush willow (Combretum molle) crude bark extracts on selected bacteria species
(2021-10) Mgonja, Frida Richard; Ally, Mohamed Hamed Sango
Treatment and control of infectious diseases in humans and animals play a vital role in prevention of illness and death. Conventional drugs treatment has been providing effective therapy for treatment of infections caused by pathogenic microorganisms; However, some do not respond to conventional therapy. Conventional therapy are expensive and have more adverse side effects. Plant based medicinal productshas been used as an alternative curative for infections caused by resistant pathogenic microorganisms, moreover, plant medicinal products have less adverse side effects. This study was conducted to assess thecrude Combretummolle bark extracts antimicrobial activityagainst three selected bacteria species. Three solvents, distilled water; ethanol and acetone were used for crude combretum molle bark extraction. The agar well diffusion method was used to assess antimicrobial activity against Streptococcus pyogenes, Pseudomonas aeruginosa and Escherichia coli. A minimum inhibition concentration (MIC) of the most active extracts was determined by the broth dilution technique. Extracts from three solvents tested demonstrated antimicrobial activity with zone of inhibition diameters ranging from 14 to 24 mm. Acetone extract was the most potent with its minimum inhibitory concentration (MIC) ranging from 1.25 to 2.50 mg/ml. There was no statistically significant difference (P>0.05) in the potency of the three extracts and standard antibiotic ciprofloxacin on the bacteria species tested. The study showed that the crude bark extract of C. molle has antimicrobial activity against all the test microorganisms.
Profiling of Haematological Indices in Relation to Body Score and Altitude Among Norwegian Goats in Morogoro, Tanzania
(Science Publishing Group, 2021-12) Ally, Mohamed Hamed Sango
Blood samples were collected from 180 apparently healthy adult Norwegian goats each 90 Norwegian goats, from high altitude and low altitude in Morogoro urban and peri-urban to assess the influence of altitude on their hematological indices. The (RBC) Red blood cells, PCV (packed cell volume), WBC (White blood cells) and HB (Hemoglobin) concentration were determined. Analysis of hematological indices was done using Automated Hematological Analyzer (Msn4s). Data on age, weight, body score, health and nutritional status were recorded for each animal. Epi-info version7.1 was used to analyze data for means, standard deviation and percentages. T-test and Chi-square were used to compare similarities between the groups. Results were compared to normal ranges of the parameters. Most parameters were within normal ranges. However significant increase in white blood cell count and decrease in hemoglobin concentration was observed from blood collected from groups of Norwegian goats located at low altitudes. Whereas the value of RBC (Red blood cells), PCV (packed cell volume) and HB (Hemoglobin) concentration in blood samples from high altitude were significantly high compared to those found at low altitude. These results revealed that, the level of hematological parameters were significantly affected by nature of areas animal located, that is altitude, although other confounding factors such as age, diseases, stress, sex, body weight and climatic condition may result to variations on the blood indices.