Browsing by Author "Nzalawahe, Jahashi"

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African animal trypanosomiasis: a systematic review on prevalence, risk factors and drug resistance in Sub-Saharan Africa
(Oxford University Press on behalf of Entomological Society of America, 2022) Okello, Ivy; Mafie, Eliakunda; Eastwood, Gillian; Nzalawahe, Jahashi; Mboera, Leonard E. G.
African animal trypanosomiasis (AAT) a parasitic disease of livestock in sub-Saharan Africa causing tremen- dous loses. Sub-Saharan continental estimation of mean prevalence in both large and small domestic animals, risk factors, tsetse and non-tsetse prevalence and drug resistance is lacking. A review and meta-analysis was done to better comprehend changes in AAT prevalence and drug resistance. Publish/Perish software was used to search and extract peer-reviewed articles in Google scholar, PubMed and CrossRef. In addition, ResearchGate and African Journals Online (AJOL) were used. Screening and selection of articles from 2000–2021 was per- formed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Articles 304 were retrieved; on domestic animals 192, tsetse and non-tsetse vectors 44, risk factors 49 and trypanocidal drug resistance 30. Prevalence varied by, host animals in different countries, diagnostic methods and species of Trypanosoma. Cattle had the highest prevalence with Ethiopia and Nigeria leading, T. congolense (11.80– 13.40%) and T. vivax (10.50–18.80%) being detected most. This was followed by camels and pigs. Common di- agnostic method used was buffy coat microscopy. However; polymerase chain reaction (PCR), CATT and ELISA had higher detection rates. G. pallidipes caused most infections in Eastern regions while G. palpalis followed by G. mortisans in Western Africa. Eastern Africa reported more non-tsetse biting flies with Stomoxys leading. Common risk factors were, body conditions, breed type, age, sex and seasons. Ethiopia and Nigeria had the highest trypanocidal resistance 30.00–35.00% and highest AAT prevalence. Isometamidium and diminazene showed more resistance with T. congolense being most resistant species 11.00–83.00%.
Evaluation of the Bachelor of Veterinary Medicine (BVM) Curriculum at Sokoine University of agriculture in Tanzania: mapping to OIE Veterinary graduate ‘Day 1 competencies
(2022-03) Komba, Erick V.G; Kipanyula, Maulilio J; Muhairwa, Amandus P.; Kazwala, Rudovick R; Makungu, Modesta J; Nzalawahe, Jahashi; Sebhatu, Tesfaalem T; Mosier, Derek A.; Schmidt, Peggy L
The World Organisation for Animal Health (OIE) provides the requirements needed for graduating veterinary professionals to be competent in the delivery of animal health services. However, significant differences in veterinary curricula across countries—attributable to differing animal health priorities and predominant types of veterinary practice—provide a challenge for veterinary schools to address these competencies adequately. As part of the OIE’s veterinary education establishment Twinning Project activities, the College of Veterinary Medicine and Biomedical Sciences (CVMBS) of Sokoine University of Agriculture (SUA) in Tanzania undertook a curriculum mapping and gap analysis to assess the extent to which the veterinary curriculum addresses OIE’s ‘Day 1 Competencies’ for graduating veterinarians. Results of the analysis indicated that all the OIE’s Day 1 Competencies (general, specific, and advanced) are addressed to some degree by the courses present in the curriculum. However, gaps in the depth and breadth of instruction were found for a number of competencies in all three categories. These findings indicate a need for addressing the gaps in the next curriculum review. This will allow the development of a stronger curriculum that will efficiently meet the national and international animal health requirements.
Prevalence and associated risk factors of African animal trypanosomiasis in cattle in Lambwe, Kenya
(Hindawi, 2022-07-14) Okello, Ivy; Mafie, Eliakunda; Eastwood, Gillian; Nzalawahe, Jahashi; Mboera, Leonard E. G.; Onyoyo, Samuel
Background. African animal trypanosomiasis (AAT) affects livestock productivity in sub-Saharan Africa. This study aimed to determine cattle AAT’s prevalence and associated risk factors in Lambwe Valley, Kenya. Methods. In a cross-sectional survey, livestock owners were recruited from four villages of Lambwe in Homa Bay, Kenya. Blood samples were collected from the jugular veins of cattle, and buffy coat smears were examined under a microscope. Parasites were further detected using polymerase chain reaction (PCR). Using a semistructured questionnaire, livestock owners were interviewed on their knowledge of AAT and control practices. Chi-square and multilevel models were used for the analysis. Results. The overall prevalence was 15.63% (71/454). Trypanosoma vivax 10.31% and T. congolense Savannah 6.01% were the common species and subspecies. A total of 61 livestock keepers were involved in the study. Of these, 91.80% (56/61) knew AAT, and 90.16% (55/61) could describe the symptoms well and knew tsetse fly bite as transmission mode. Self-treatment (54.09%; 33/61) was common, with up to 50.00% of the farmers using drugs frequently. Isometamidium (72.13%; 44/61) and diminazene (54.09%; 33/61) were drugs frequently used. Although 16.39% (10/61) of the farmers claimed to use chemoprophylactic treatment, 6/10 did not use the right drugs. Animals (92.1%; 58/63) with clinical signs had positive infections. Villages closer to the national park recorded a higher prevalence. Infections were higher in cattle owned by those self-treating (27.23%; 58/213), those using drug treatment without vector control (27.62%; 50/181), those using single-drug therapy, and those practicing communal grazing (20.00%; 59/ 295). Clinical signs strongly associate with positive infections under multilevel modeling. Conclusion. Cattle trypanosomiasis is prevalent in the Lambwe region of Kenya. This is influenced by inappropriate control practices, communal grazing, and the proximity of farms to the national park. In addition, clinical signs of the disease have a strong association with infections
Role of domestic animals in the epidemiology of human African trypanosomiasis (hat) in Kigoma –Tanzania
(Sokoine University of Agriculture, 2010) Nzalawahe, Jahashi
Human African trypanosomiasis (HAT) is fatal if untreated and causes severe morbidity. In Tanzania HAT is caused by Trypanosoma b. rhodesiense. Trypanosomiasis in livestock is the major impediment to livestock farming and it limits the full potential of agricultural development in Tanzania. This study was undertaken in Kasulu district of Kigoma region, an area that is endemic for both human and animal trypanosomiasis. This study aimed to determine the prevalence of trypanosomiasis in domestic animals and the potential of these domestic animals as reservoirs of human infective trypanosomes. This study was undertaken in four villages namely Kagerankanda, Mvinza, Makere and Mvugwe. Eleven cattle samples (11%) of the 100 cattle sampled in the four villages were detected as positive by PCR using the ITS1 primers that identify trypanosomes to the level of species and subspecies. These were recognized as six Trypanosoma vivax (4%) and five Trypanosoma congolense forest type (3.33%). Cattle were more susceptible to trypanosome infection compared to other domestic animals like goats and dogs, because trypanosomes were not detected in these two species of domestic animals. Since Trypanosoma brucei species was not detected in this study, these results suggested that domestic animals that are kept in the study area do not harbour human infective trypanosomes and trypanosomiasis is prevalent in cattle.iii DECLARATION I, Jahashi Nzalawahe, do hereby declare to Senate of Sokoine University of Agricultur