Role of p53 and Rb in liver cancer

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Date

2008

Journal Title

Journal ISSN

Volume Title

Publisher

Sokoine University of Agriculture

Abstract

Liver, the largest single organ in the body plays a central role in metabolism with a number of functions including, synthesis, storage and redistribution of carbohydrates, fats, and vitamins. Also, the liver produces large numbers of serum proteins including albumin, acute-phase proteins, enzymes and cofactors (1). Anatomically and functionally, the liver can be divided into hepatic lobules which are functional units and hexagonal in shape (Figure 1), (2).

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Thesis

Keywords

Serum proteins, p53 and Rb, Liver cancer, Albumin, Enzymes and cofactors

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