Immunohistochemical detection of Mycoplasma mucoid mucoid small colony type in lungs of slaughtered cattle at Morogoro slaughterhouse, Tanzania

dc.contributor.authorMalago, J. J.
dc.contributor.authorMlay, J. D.
dc.date.accessioned2018-06-17T10:19:35Z
dc.date.available2018-06-17T10:19:35Z
dc.date.issued2015
dc.descriptionTanzania Veterinary Journalen_US
dc.description.abstractDiagnosis of contagious bovine pleuropneumonia (CBPP) in carrier animals remains to be a challenge in developing countries partly because of lack of diagnostic tools that can detect asymptomatic animals. As a result many apparently healthy animals pose a potential impending epidemic in periods of stress. We examined condemned lungs with CBPP-like lesions from apparently healthy slaughtered animals to confirm presence of the disease in these animals. A total of 13 lungs collected at abattoir were examined immunohistochemically using 3H12 and 6E3 monoclonal antibodies against Mycoplasma mycoides mycoides (MmmSC), the causative agent of CBPP. Both 3H12 and 6E3 antibodies detected the MmmSC antigens in all the 13 lungs in bronchial, bronchiolar and alveolar epithelia, bronchial glands, bronchial cartilage, and in alveoli. We conclude that CBPP is still present in various places of Tanzania, posing a threat to livestock production and that immunohistochemistry can be an efficient diagnostic method to confirm presence of the disease in asymptomatic healthy animals passed for slaughter.en_US
dc.identifier.urihttps://www.suaire.sua.ac.tz/handle/123456789/2369
dc.language.isoenen_US
dc.publisherTanzania Veterinary Journalen_US
dc.subjectCBPPen_US
dc.subjectCattleen_US
dc.subjectMonoclonal antibodyen_US
dc.subjectLung parenchymaen_US
dc.subjectMmmSC antigensen_US
dc.subjectImmunohistochemistryen_US
dc.titleImmunohistochemical detection of Mycoplasma mucoid mucoid small colony type in lungs of slaughtered cattle at Morogoro slaughterhouse, Tanzaniaen_US
dc.typeArticleen_US
dc.urlhttps://www.ajol.info/index.php/tvj/article/view/158604en_US

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